期刊
VIRUS RESEARCH
卷 135, 期 1, 页码 10-21出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.virusres.2008.02.001
关键词
lyssaviruses; rabies; phylogeny; Lagos bat virus; rabies-related; taxonomy
类别
Lagos bat virus (LBV) belongs to genotype 2 of the Lyssavirus genus. The complete nucleoprotein (N), phosphoprotein (P), matrixprotein (M) and glycoprotein (G) genes of 13 LBV isolates were sequenced and phylogenetically compared with other lyssavirus representatives. The results identified three different lineages of LBV. One of these lineages demonstrated sufficient sequence diversity to be considered a new lyssavirus genotype (Dakar bat lyssavirus). The suggested quantitative separation of lyssavirus genotypes using the N, P, M and G genes was also investigated using P-distances matrixes. Results indicated that the current criteria should be revised since overlaps between intergenotypic and intragenotypic variation occur. (c) 2008 Elsevier B.V. All rights reserved.
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