期刊
VIRUS GENES
卷 48, 期 1, 页码 184-188出版社
SPRINGER
DOI: 10.1007/s11262-013-0985-0
关键词
Tick-borne encephalitis virus (TBEV); Slovakia; Complete genome sequence; Myodes glareolus; Ixodes ricinus
资金
- Federal Ministry of Education and Research (BMBF) [01KI 0712]
The full genome sequences of three tick-borne encephalitis virus strains, two isolated from Ixodes ricinus ticks and one from the brain of a bank vole, Myodes glareolus, originating from the Slovak Republic were determined. Nucleotide sequences were found to be very similar (> 99.5 % nt-identity) with only one distinct amino acid (aa) difference to each other. They all shared 30 aa-changes when compared to type strain Neudoerfl, isolated in neighboring Austria. An internal poly(A)-stretch similar to that of strain Neudoerfl was found only in TBEV strain 114 from a tick. Despite this heterogeneity in the 3'-NCR, the high level of sequence identity was striking, indicating a low rate of nucleotide substitutions of TBEV strains in Slovakia and no obvious relation to the host species.
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