期刊
VIROLOGY
卷 388, 期 1, 页码 8-14出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.virol.2009.03.019
关键词
Talpid; Soricid; Phylogeny; Host switching; Hantavirus
类别
资金
- NCRR NIH HHS [P20 RR018727, P20RR018727, G12 RR003061-23, G12RR003061, P20 RR018727-05, G12 RR003061] Funding Source: Medline
- NIAID NIH HHS [R01 AI075057-01A1, R01 AI075057, R01AI075057] Funding Source: Medline
A genetically distinct hantavirus, designated Oxbow virus (OXBV), was detected in tissues of an American shrew mole (Neurotrichus gibbsii), captured in Gresham, Oregon, in September 2003. Pairwise analysis of full-length S- and M- and partial L-segment nucleotide and amino acid sequences of OXBV indicated low sequence similarity with rodent-borne hantaviruses. Phylogenetic analyses using maximum-likelihood and Bayesian methods, and host-parasite evolutionary comparisons, showed that OXBV and Asama virus, a hantavirus recently identified from the Japanese Shrew mole (Urotrichus talpoides), were related to soricine shrew-borne hantaviruses from North America and Eurasia, respectively, Suggesting parallel evolution associated with cross-species transmission. (C) 2009 Elsevier Inc. All rights reserved.
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