相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。The Achilles' heel of senescent cells: from transcriptome to senolytic drugs
Yi Zhu et al.
AGING CELL (2015)
Cellular Senescence in Type 2 Diabetes: A Therapeutic Opportunity
Allyson K. Palmer et al.
DIABETES (2015)
JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age
Ming Xu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Insulin resistance and impaired adipogenesis
Birgit Gustafson et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2015)
White-to-brown metabolic conversion of human adipocytes by JAK inhibition
Annie Moisan et al.
NATURE CELL BIOLOGY (2015)
Growth hormone action predicts age-related white adipose tissue dysfunction and senescent cell burden in mice
Michael B. Stout et al.
AGING-US (2014)
The role of JAK-STAT signaling in adipose tissue function
Allison J. Richard et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2014)
Adipogenic Differentiation Is Impaired in Replicative Senescent Human Subcutaneous Adipose-Derived Stromal/Progenitor Cells
Maria C. Mitterberger et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2014)
Mechanisms and Metabolic Implications of Regional Differences among Fat Depots
Tamara Tchkonia et al.
CELL METABOLISM (2013)
Effects of the activin A-myostatin-follistatin system on aging bone and muscle progenitor cells
Matthew Bowser et al.
EXPERIMENTAL GERONTOLOGY (2013)
Cellular senescence and the senescent secretory phenotype: therapeutic opportunities
Tamara Tchkonia et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
A complex secretory program orchestrated by the inflammasome controls paracrine senescence
Juan Carlos Acosta et al.
NATURE CELL BIOLOGY (2013)
Perilipin1 promotes unilocular lipid droplet formation through the activation of Fsp27 in adipocytes
Zhiqi Sun et al.
NATURE COMMUNICATIONS (2013)
A senescent cell bystander effect: senescence-induced senescence
Glyn Nelson et al.
AGING CELL (2012)
The Intersection Between Aging and Cardiovascular Disease
Brian J. North et al.
CIRCULATION RESEARCH (2012)
Cell Autonomous Lipin 1 Function Is Essential for Development and Maintenance of White and Brown Adipose Tissue
Karim Nadra et al.
MOLECULAR AND CELLULAR BIOLOGY (2012)
A Double-Blind, Placebo-Controlled Trial of Ruxolitinib for Myelofibrosis
Srdan Verstovsek et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
JAK Inhibition with Ruxolitinib versus Best Available Therapy for Myelofibrosis
Claire Harrison et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
Ncb5or Deficiency Increases Fatty Acid Catabolism and Oxidative Stress
Ming Xu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
Darren J. Baker et al.
NATURE (2011)
Obesity, insulin resistance and free fatty acids
Guenther Boden
CURRENT OPINION IN ENDOCRINOLOGY DIABETES AND OBESITY (2011)
Fat tissue, aging, and cellular senescence
Tamara Tchkonia et al.
AGING CELL (2010)
Preclinical characterization of the selective JAK1/2 inhibitor INCB018424: therapeutic implications for the treatment of myeloproliferative neoplasms
Alfonso Quintas-Cardama et al.
BLOOD (2010)
Activin A Plays a Critical Role in Proliferation and Differentiation of Human Adipose Progenitors
Laure-Emmanuelle Zaragosi et al.
DIABETES (2010)
Characterization of the Ligand Binding Functionality of the Extracellular Domain of Activin Receptor Type IIB
Dianne Sako et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Aging, Depot Origin, and Preadipocyte Gene Expression
Mark J. Cartwright et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2010)
Safety and Efficacy of INCB018424, a JAK1 and JAK2 Inhibitor, in Myelofibrosis.
Srdan Verstovsek et al.
NEW ENGLAND JOURNAL OF MEDICINE (2010)
A Human-Like Senescence-Associated Secretory Phenotype Is Conserved in Mouse Cells Dependent on Physiological Oxygen
Jean-Philippe Coppe et al.
PLOS ONE (2010)
Regional differences in cellular mechanisms of adipose tissue gain with overfeeding
Yourka D. Tchoukalova et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Gluttony, sloth and the metabolic syndrome: a roadmap to lipotoxicity
Roger H. Unger et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2010)
Age-related changes in total and regional fat distribution
Jennifer L. Kuk et al.
AGEING RESEARCH REVIEWS (2009)
Saturated with fat: new parspectives on lipotoxicity
Jeanne Garbarino et al.
CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE (2009)
The structure of myostatin: follistatin 288: insights into receptor utilization and heparin binding
Jennifer N. Cash et al.
EMBO JOURNAL (2009)
Interferon γ Attenuates Insulin Signaling, Lipid Storage, and Differentiation in Human Adipocytes via Activation of the JAK/STAT Pathway
Fiona C. McGillicuddy et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
The biology of activin: recent advances in structure, regulation and function
Yin Xia et al.
JOURNAL OF ENDOCRINOLOGY (2009)
Transgenic expression of a myostatin inhibitor derived from follistatin increases skeletal muscle mass and ameliorates dystrophic pathology in mdx mice
Masashi Nakatani et al.
FASEB JOURNAL (2008)
Adipose tissue lipin-1 expression is correlated with peroxisome proliferator-activated receptor alpha gene expression and insulin sensitivity in healthy young men
Jimmy Donkor et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2008)
Dynamics of fat cell turnover in humans
Kirsty L. Spalding et al.
NATURE (2008)
Adipogenic capacity and the susceptibility to type 2 diabetes and metabolic syndrome
May-Yun Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor
Jean-Philippe Coppe et al.
PLOS BIOLOGY (2008)
Increased TNFα and CCAAT/enhancer-binding protein homologous protein with aging predispose preadipocytes to resist adipogenesis
Tamara Tchkonia et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2007)
Aging in adipocytes: Potential impact of inherent, depot-specific mechanisms
Mark J. Cartwright et al.
EXPERIMENTAL GERONTOLOGY (2007)
Aging results in paradoxical susceptibility of fat cell progenitors to lipotoxicity
Wen Guo et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2007)
Cellular senescence: when bad things happen to good cells
Judith Campisi et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Increased CUG triplet repeat-binding protein-1 predisposes to impaired adipogenesis with aging
Iordanes Karagiannides et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
A 3-year longitudinal study on body composition changes in the elderly: Role of physical exercise
Comasia Addolorata Raguso et al.
CLINICAL NUTRITION (2006)
Lipotoxicity, overnutrition and energy metabolism in aging
Marc Slawik et al.
AGEING RESEARCH REVIEWS (2006)
Cytokines promote Wnt signaling and inflammation and impair the normal differentiation and lipid accumulation in 3T3-L1 preadipocytes
B Gustafson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Prevalence of diabetes and impaired fasting glucose in adults in the US population - National Health and Nutrition Examination Survey 1999-2002
Catherine C. Cowie et al.
DIABETES CARE (2006)
Increased caveolin-1, a cause for the declined adipogenic potential of senescent human mesenchymal stem cells
JS Park et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2005)
Abundance of two human preadipocyte subtypes with distinct capacities for replication, adipogenesis, and apoptosis varies among fat depots
T Tchkonia et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2005)
Regulation of muscle mass by myostatin
SJ Lee
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY (2004)
Triglyceride accumulation protects against fatty acid-induced lipotoxicity
LL Listenberger et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
SB-431542 is a potent and specific inhibitor of transforming growth factor-β superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7
GJ Inman et al.
MOLECULAR PHARMACOLOGY (2002)
分享论文
