相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Sequence-structure based phylogeny of GPCR Class A Rhodopsin receptors
Kavita Kumari Kakarala et al.
MOLECULAR PHYLOGENETICS AND EVOLUTION (2014)
Neuronal targets for reducing mutant huntingtin expression to ameliorate disease in a mouse model of Huntington's disease
Nan Wang et al.
NATURE MEDICINE (2014)
Anatomical Transcriptome of G Protein-Coupled Receptors Leads to the Identification of a Novel Therapeutic Candidate GPR52 for Psychiatric Disorders
Hidetoshi Komatsu et al.
PLOS ONE (2014)
Drugging unconventional targets: insights from Huntington's disease
Shenliang Yu et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2014)
TR-FRET Assays for Endogenous Huntingtin Protein Level in Mouse Cells
Yijian Liang et al.
JOURNAL OF HUNTINGTONS DISEASE (2014)
A novel human embryonic stem cell-derived Huntington's disease neuronal model exhibits mutant huntingtin (mHTT) aggregates and soluble mHTT-dependent neurodegeneration
Boxun Lu et al.
FASEB JOURNAL (2013)
Regulation of Feedback between Protein Kinase A and the Proteasome System Worsens Huntington's Disease
Jiun-Tsai Lin et al.
MOLECULAR AND CELLULAR BIOLOGY (2013)
Circular Intronic Long Noncoding RNAs
Yang Zhang et al.
MOLECULAR CELL (2013)
Proteostasis of polyglutamine varies among neurons and predicts neurodegeneration
Andrey S. Tsvetkov et al.
NATURE CHEMICAL BIOLOGY (2013)
Identification of NUB1 as a suppressor of mutant Huntingtin toxicity via enhanced protein clearance
Boxun Lu et al.
NATURE NEUROSCIENCE (2013)
A RabGAP Regulates Life-Cycle Duration via Trimeric G-protein Cascades in Dictyostelium discoideum
Hidekazu Kuwayama et al.
PLOS ONE (2013)
Rapgef2 Connects GPCR-Mediated cAMP Signals to ERK Activation in Neuronal and Endocrine Cells
Andrew C. Emery et al.
SCIENCE SIGNALING (2013)
Six-month partial suppression of Huntingtin is well tolerated in the adult rhesus striatum
Richard Grondin et al.
BRAIN (2012)
Human Embryonic Stem Cell-Derived GABA Neurons Correct Locomotion Deficits in Quinolinic Acid-Lesioned Mice
Lixiang Ma et al.
CELL STEM CELL (2012)
Induced Pluripotent Stem Cells from Patients with Huntington's Disease Show CAG-Repeat-Expansion-Associated Phenotypes
CELL STEM CELL (2012)
Signaling through the neuropeptide GPCR PAC1 induces neuritogenesis via a single linear cAMP- and ERK-dependent pathway using a novel cAMP sensor
Andrew C. Emery et al.
FASEB JOURNAL (2012)
Native Mutant Huntingtin in Human Brain EVIDENCE FOR PREVALENCE OF FULL-LENGTH MONOMER
Ellen Sapp et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Long Noncoding RNAs with snoRNA Ends
Qing-Fei Yin et al.
MOLECULAR CELL (2012)
A Genome-Scale RNA-Interference Screen Identifies RRAS Signaling as a Pathologic Feature of Huntington's Disease
John P. Miller et al.
PLOS GENETICS (2012)
PATHOPHYSIOLOGY OF HUNTINGTON'S DISEASE: TIME-DEPENDENT ALTERATIONS IN SYNAPTIC AND RECEPTOR FUNCTION
L. A. Raymond et al.
NEUROSCIENCE (2011)
Single-step detection of mutant huntingtin in animal and human tissues: A bioassay for Huntington's disease
Andreas Weiss et al.
ANALYTICAL BIOCHEMISTRY (2009)
Nonallele-specific Silencing of Mutant and Wild-type Huntingtin Demonstrates Therapeutic Efficacy in Huntington's Disease Mice
Ryan L. Boudreau et al.
MOLECULAR THERAPY (2009)
Rhes, a Striatal Specific Protein, Mediates Mutant-Huntingtin Cytotoxicity
Srinivasa Subramaniam et al.
SCIENCE (2009)
Novel targets for Huntington's disease in an mTOR-independent autophagy pathway
Andrea Williams et al.
NATURE CHEMICAL BIOLOGY (2008)
Differential roles of Rap1 and Rap2 small GTPases in neurite retraction and synapse elimination in hippocampal spiny neurons
Zhanyan Fu et al.
JOURNAL OF NEUROCHEMISTRY (2007)
CHIP protects from the neurotoxicity of expanded and wild-type ataxin-1 and promotes their ubiquitination and degradation
Ismael Al-Ramahi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Screening for target Rabs of TBC (Tre-2/Bub2/Cdc16) domain-containing proteins based on their Rab-binding activity
Takashi Itoh et al.
GENES TO CELLS (2006)
Huntingtin associates with acidic phospholipids at the plasma membrane
KB Kegel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Time course of early motor and neuropathological anomalies in a knock-in mouse model of Huntington's disease with 140 CAG repeats
LB Menalled et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2003)
cAMP analog mapping of Epac1 and cAMP kinase - Discriminating analogs demonstrate that Epac and cAMP kinase act synergistically to promote PC-12 cell neurite extension
AE Christensen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Unfolding the role of protein misfolding in neurodegenerative diseases
C Soto
NATURE REVIEWS NEUROSCIENCE (2003)
A novel Epac-specific cAMP analogue demonstrates independent regulation of Rap1 and ERK
JM Enserink et al.
NATURE CELL BIOLOGY (2002)
Centrosome disorganization in fibroblast cultures derived from R6/2 Huntington's disease (HD) transgenic mice and HD patients
K Sathasivam et al.
HUMAN MOLECULAR GENETICS (2001)
New anti-huntingtin monoclonal antibodies: Implications for huntingtin conformation and its binding proteins
J Ko et al.
BRAIN RESEARCH BULLETIN (2001)
Dominant phenotypes produced by the HD mutation in STHdhQ111 striatal cells
F Trettel et al.
HUMAN MOLECULAR GENETICS (2000)