相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。A Combined Proteomics/Genomics Approach Links Hepatitis C Virus Infection with Nonsense-Mediated mRNA Decay
Holly R. Ramage et al.
MOLECULAR CELL (2015)
Mutations in a translation initiation factor identify the target of a memory-enhancing compound
Yusuke Sekine et al.
SCIENCE (2015)
The small molecule ISRIB reverses the effects of elF2α phosphorylation on translation and stress granule assembly
Carmela Sidrauski et al.
ELIFE (2015)
Insights into the Architecture of the elF2Bα/β/δ Regulatory Subcomplex
Andrew M. Bogorad et al.
BIOCHEMISTRY (2014)
Axonally Synthesized ATF4 Transmits a Neurodegenerative Signal across Brain Regions
Jimena Baleriola et al.
CELL (2014)
P7C3 Neuroprotective Chemicals Function by Activating the Rate-Limiting Enzyme in NAD Salvage
Gelin Wang et al.
CELL (2014)
A new function and complexity for protein translation initiation factor eIF2B
Martin D. Jennings et al.
CELL CYCLE (2014)
Analysis of the subunit organization of the eIF2B complex reveals new insights into its structure and regulation
Noel C. Wortham et al.
FASEB JOURNAL (2014)
Unraveling the mechanism of cell death induced by chemical fibrils
Olivier Julien et al.
NATURE CHEMICAL BIOLOGY (2014)
Therapeutic modulation of eIF2α phosphorylation rescues TDP-43 toxicity in amyotrophic lateral sclerosis disease models
Hyung-Jun Kim et al.
NATURE GENETICS (2014)
Translational control of mGluR-dependent long-term depression and object-place learning by eIF2α
Gonzalo Viana Di Prisco et al.
NATURE NEUROSCIENCE (2014)
Functional genomics platform for pooled screening and generation of mammalian genetic interaction maps
Martin Kampmann et al.
NATURE PROTOCOLS (2014)
ER Stress-Induced eIF2-alpha Phosphorylation Underlies Sensitivity of Striatal Neurons to Pathogenic Huntingtin
Julia Leitman et al.
PLOS ONE (2014)
eIF2B is a decameric guanine nucleotide exchange factor with a γ2ε2 tetrameric core
Yuliya Gordiyenko et al.
NATURE COMMUNICATIONS (2014)
A Systematic Mammalian Genetic Interaction Map Reveals Pathways Underlying Ricin Susceptibility
Michael C. Bassik et al.
CELL (2013)
Next-Generation NAMPT Inhibitors Identified by Sequential High-Throughput Phenotypic Chemical and Functional Genomic Screens
Christina J. Matheny et al.
CHEMISTRY & BIOLOGY (2013)
eIF2B promotes eIF5 dissociation from eIF2•GDP to facilitate guanine nucleotide exchange for translation initiation
Martin D. Jennings et al.
GENES & DEVELOPMENT (2013)
Suppression of eIF2α kinases alleviates Alzheimer's disease-related plasticity and memory deficits
Tao Ma et al.
NATURE NEUROSCIENCE (2013)
Integrated platform for genome-wide screening and construction of high-density genetic interaction maps in mammalian cells
Martin Kampmann et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Monitoring Drug Target Engagement in Cells and Tissues Using the Cellular Thermal Shift Assay
Daniel Martinez Molina et al.
SCIENCE (2013)
Oral Treatment Targeting the Unfolded Protein Response Prevents Neurodegeneration and Clinical Disease in Prion-Infected Mice
Julie A. Moreno et al.
SCIENCE TRANSLATIONAL MEDICINE (2013)
Pharmacological brake-release of mRNA translation enhances cognitive memory
Carmela Sidrauski et al.
ELIFE (2013)
elF2γ Mutation that Disrupts elF2 Complex Integrity Links Intellectual Disability to Impaired Translation Initiation
Guntram Borck et al.
MOLECULAR CELL (2012)
Sustained translational repression by eIF2α-P mediates prion neurodegeneration
Julie A. Moreno et al.
NATURE (2012)
The human translation initiation multi-factor complex promotes methionyl-tRNA(i) binding to the 40S ribosomal subunit
Masaaki Sokabe et al.
NUCLEIC ACIDS RESEARCH (2012)
The Mechanism of Eukaryotic Translation Initiation: New Insights and Challenges
Alan G. Hinnebusch et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2012)
Phosphorylation of eIF2 Facilitates Ribosomal Bypass of an Inhibitory Upstream ORF to Enhance CHOP Translation
Lakshmi Reddy Palam et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Rapid Synthesis of the X-Linked Mental Retardation Protein OPHN1 Mediates mGluR-Dependent LTD through Interaction with the Endocytic Machinery
Nael Nadif Kasri et al.
NEURON (2011)
The GCN2-ATF4 pathway is critical for tumour cell survival and proliferation in response to nutrient deprivation
Jiangbin Ye et al.
EMBO JOURNAL (2010)
Regulation of the Unfolded Protein Response by eIF2Bδ Isoforms
Leenus Martin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
The β/Gcd7 Subunit of Eukaryotic Translation Initiation Factor 2B (eIF2B), a Guanine Nucleotide Exchange Factor, Is Crucial for Binding eIF2 In Vivo
Kamal Dev et al.
MOLECULAR AND CELLULAR BIOLOGY (2010)
Flavonol Activation Defines an Unanticipated Ligand-Binding Site in the Kinase-RNase Domain of IRE1
R. Luke Wiseman et al.
MOLECULAR CELL (2010)
eIF5 has GDI activity necessary for translational control by eIF2 phosphorylation
Martin D. Jennings et al.
NATURE (2010)
Turning enzymes ON with small molecules
Julie A. Zorn et al.
NATURE CHEMICAL BIOLOGY (2010)
The h subunit of eIF3 promotes reinitiation competence during translation of mRNAs harboring upstream open reading frames
Bijoyita Roy et al.
RNA (2010)
An Upstream Open Reading Frame Regulates Translation of GADD34 during Cellular Stresses That Induce eIF2α Phosphorylation
Yun-Young Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
eIF3a cooperates with sequences 5 ' of uORF1 to promote resumption of scanning by post-termination ribosomes for reinitiation on GCN4 mRNA
Bela Szamecz et al.
GENES & DEVELOPMENT (2008)
MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification
Juergen Cox et al.
NATURE BIOTECHNOLOGY (2008)
eIF3j is located in the decoding center of the human 40S ribosomal subunit
Christopher S. Fraser et al.
MOLECULAR CELL (2007)
Mutations linked to Leukoencephalopathy with vanishing white matter impair the function of the eukaryotic initiation factor 2B complex in diverse ways
W Li et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells
KM Vattem et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Cre-lox-regulated conditional RNA interference from transgenes
A Ventura et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response
PD Lu et al.
JOURNAL OF CELL BIOLOGY (2004)
Inducible enhancement of memory storage and synaptic plasticity in transgenic mice expressing an inhibitor of ATF4 (CREB-2) and C/EBP proteins
A Chen et al.
NEURON (2003)
An integrated stress response regulates amino acid metabolism and resistance to oxidative stress
HP Harding et al.
MOLECULAR CELL (2003)
Subunits of the translation initiation factor eIF2B are mutant in leukoencephalopathy with vanishing white matter
PAJ Leegwater et al.
NATURE GENETICS (2001)
Tight binding of the phosphorylated α subunit of initiation factor 2 (eIF2α) to the regulatory subunits of guanine nucleotide exchange factor eIF2B is required for inhibition of translation initiation
T Krishnamoorthy et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
Characterization of the mammalian initiation factor eIF2B complex as a GDP dissociation stimulator protein
DD Williams et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2α
I Novoa et al.
JOURNAL OF CELL BIOLOGY (2001)
Regulated translation initiation controls stress-induced gene expression in mammalian cells
HP Harding et al.
MOLECULAR CELL (2000)
分享论文
