期刊
VETERINARY PATHOLOGY
卷 49, 期 3, 页码 423-439出版社
SAGE PUBLICATIONS INC
DOI: 10.1177/0300985811429313
关键词
animal models; Bacille Calmette-Guerin; granuloma; Mycobacterium tuberculosis; pathogenesis; tuberculosis
Mycobacterium tuberculosis is an old enemy of the human race, with evidence of infection observed as early as 5000 years ago. Although more host-restricted than Mycobacterium bovis, which can infect all warm-blooded vertebrates, M. tuberculosis can infect, and cause morbidity and mortality in, several veterinary species as well. As M. tuberculosis is one of the earliest described bacterial pathogens, the literature describing this organism is vast and overwhelming. This review strives to distill what is currently known about this bacterium and the disease it causes for the veterinary pathologist.
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