期刊
VETERINARY MICROBIOLOGY
卷 163, 期 1-2, 页码 177-183出版社
ELSEVIER
DOI: 10.1016/j.vetmic.2012.12.019
关键词
Porcine circovirus type 2 (PCV2); Vaccination; Mutant PCV2; Porcine parvovirus type 2 (PPV2)
资金
- CAPES [5548110]
Porcine circovirus (PCV) type 2b (PCV2b) emerged in North America in 2005-2006. During May of 2012, PCVAD occurred in 10-18-week-old pigs in two farms within a production system that routinely vaccinated against PCV2. Both farms received replacement gilts from the same multiplier. A mutant PCV2b strain not previously present in North America was identified. The strain was found to be 99.9% identical to a recently described mutant PCV2 isolate reported in China in 2010 and thought to be more virulent than classical PCV2a or PCV2b strains. It is possible that the current PCV2a-based commercial vaccines are not fully protective against this new strain. In addition, emerging porcine parvovirus type 2 (PPV2) was detected in 55% of the serum samples (73/132), perhaps implying that PPV2 could be a cofactor in cases of PCVAD. (C) 2012 Elsevier B.V. All rights reserved.
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