期刊
VETERINARY MICROBIOLOGY
卷 149, 期 3-4, 页码 504-507出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.vetmic.2010.11.025
关键词
Anaplasma phagocytophilum; Cattle; Tick
资金
- Japan Society for the Promotion of Science (JSPS)
- Global COE (Centers of Excellence) through Hokkaido University
- Bio-oriented Technology Research Advancement Institution (BRAIN)
- Grants-in-Aid for Scientific Research [22591116, 22405036, 23248051] Funding Source: KAKEN
The tick-borne pathogen, Anaplasma phagocytophilum (A. phagocytophilum), the causative agent of human granulocytic anaplasmaposis (HGA), is increasingly becoming a public health concern as an aetiological agent for emerging infectious disease. We found A. phagocytophilum infection in a pooled sample of field-collected Ixodes persulcatus (I. persulcatus) ticks from one district in Hokkaido, Japan. Thus, to further investigate the prevalence in field-collected ticks, we used PCR assays targeting the A. phagocytophilum gene encoding 44 kDa major outer membrane protein (p44) for screening of I. persulcatus ticks and samples from cattle from pastures. Out of the 281 I. persulcatus ticks, 20 (7.1%) were found to harbor A. phagocytophilum DNA. The infection rate for A. phagocytophilum in cattle was 3.4% (42/1251). In future studies, it will be necessary to investigate effects of the infection in order to understand its pathogenesis of A. phagocytophilum in domestic animals. Crown Copyright (C) 2010 Published by Elsevier B.V. All rights reserved.
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