The relationship between equine and human West Nile virus disease occurrence

Cases of human and equine West Nile virus (WNV) disease reported in Texas in 2002 were analyzed to assess their temporal relationship. For each human case with a known residential location, the closest equine case (within a 5 km radius) was selected. A total of 80 human-equine case pairs were identified, 51 (64%) of which were located in urban areas. Dates-of-onset of human and equine cases were positively correlated (r(SP) = 0.494, P < 0.001). Although overall there was no significant (P = 0.207) difference between the dates-of-onset of human and equine cases, in urban areas of Texas equine cases were reported significantly (P = 0.011) earlier (August 7) than corresponding human cases (August 19). Monitoring equine populations that are susceptible to WNV disease within close proximity to urban human populations might be useful for predicting disease risk in human populations. (C) 2007 Elsevier B.V All rights reserved.