期刊
VETERINARY JOURNAL
卷 198, 期 3, 页码 723-724出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.tvjl.2013.09.008
关键词
Common European adder (Vipera berus berus); Acute kidney injury; Urine; Creatinine
资金
- Finnish Veterinary Association
Envenomation by the common European adder (Vipera berus berus) causes clinical renal injury in dogs. In this study, serum concentrations of albumin, creatinine, total protein and urea were measured in 32 dogs bitten by adders. Urinary creatinine, protein, and retinol binding protein 4 concentrations, and the activities of gamma-glutamyl transpeptidase (GGT) and alkaline phosphatase (ALP), were measured in 32 affected dogs and 23 healthy controls. Clinical assessment was conducted with a grading scale and a renal function score was applied to classify dogs based on laboratory findings. Urinary protein:creatinine, GGT:creatinine and ALP:creatinine ratios appear to be useful in evaluating renal impairment in dogs with adder envenomation. Increasing kidney function score was correlated with increased urinary ALP:creatinine and GGT:creatinine ratios. (C) 2013 Elsevier Ltd. All rights reserved.
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