期刊
VETERINARY JOURNAL
卷 196, 期 1, 页码 114-115出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.tvjl.2012.08.002
关键词
Pig; Salmonella enterica serovar Typhimurium; IgG; IgA; Colostrum
资金
- Ministry of Agriculture of the Czech Republic [QH81062, MZe 0002716202]
- Ministry of Education, Youth and Sports of the Czech Republic (AdmireVet Project) [CZ.1.05/2.1.00/01.0006, ED0006/01/01]
The significance of maternal immunity against non-typhoid Salmonella spp. acquired by piglets via colostrum and milk was evaluated in a Salmonella enterica serovar Typhimurium challenge experiment. Piglets from sows vaccinated with an experimental inactivated vaccine exhibited high levels of serum immunoglobulins G and A against S. Typhimurium 4 days after birth, just prior to experimental oral challenge. The S. Typhimurium load in the ileal and caecal wall of piglets 3 days after experimental inoculation was lower by a 2-log magnitude compared to unvaccinated controls. Such a vaccine, delivering colostral/lactogenic immunity to piglets thus has the potential to reduce the prevalence non-typhoid Salmonella spp. infection. (c) 2012 Elsevier Ltd. All rights reserved.
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