期刊
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY
卷 157, 期 3-4, 页码 142-148出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.vetimm.2013.11.009
关键词
Aeromonas; Innate immune system; Fish; Silver catfish; Bacteria; Hematology
资金
- Fundacao de Amparo a Pesquisa do Estado do Rio Grande do Sul (FAPERGS/PRONEX)
- Ministerio da Pesca/Ministerio da Ciencia e Tecnologia/FINEP
- Conselho Nacional de Pesquisa e Desenvolvimento Cientifico (CNPq)
- CNPq
- CAPES (Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior)
The aim of this study was to evaluate the activity of eugenol against the fish pathogen Aeromonas hydrophila and eugenol's effect on hematological and natural immune parameters in silver catfish (Rhamdia quelen). In vitro, eugenol showed weak activity against A. hydrophila, but in vivo, at a subinhibitory concentration (10 mg L-1), it promoted survival in infected silver catfish. Eugenol (50 mu g mL(-1)) reduced the hemolytic activity of A. hydrophila supernatant in vitro in fish erythrocytes. Subjecting catfish to eugenol baths (5 and 10 mg L-1) for five days did not alter the hematological and immunological parameters studied in this work. Based on these results, eugenol can be used to treat or prevent bacterial diseases in fish. (C) 2013 Elsevier B.V. All rights reserved.
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