期刊
VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE
卷 43, 期 5, 页码 1039-+出版社
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.cvsm.2013.05.002
关键词
Cat; Species differences; Glucuronidation; Pharmacokinetics
资金
- William R. Jones Endowed Chair in Veterinary Medicine at Washington State University
Although it is widely appreciated that cats respond differently to certain drugs compared with other companion animal species, the causes of these differences are poorly understood. This article evaluates published evidence for altered drug effects in cats, focusing on pharmacokinetic differences between cats, dogs, and humans, and the molecular mechanisms underlying these differences. More work is needed to better understand drug metabolism and disposition differences in cats, thereby enabling more rational prescribing of existing medications, and the development of safer drugs for this species.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据