期刊
VETERINARY CLINICS OF NORTH AMERICA-EQUINE PRACTICE
卷 29, 期 3, 页码 689-+出版社
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.cveq.2013.09.001
关键词
Quarter Horse; Hereditary; Skin tearing; Collagen; HERDA; DNA testing
Hereditary equine regional dermal asthenia is a form of Ehlers-Danlos syndrome, and has an autosomal recessive mode of inheritance. Affected horses are typically born normal and develop lesions within the first 2 years of life. The most common symptoms of the disease include stretchy, loose skin that feels doughy or mushy. More severely affected horses experience spontaneous skin sloughing and extensive lacerations, hematomas, and seromas from minor trauma. Affected horses have a higher than expected incidence of corneal ulcers. DNA testing can normal, establish carrier and affected status. Palliative therapy is available, but no curative treatment exists.
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