期刊
VECTOR-BORNE AND ZOONOTIC DISEASES
卷 13, 期 12, 页码 877-883出版社
MARY ANN LIEBERT, INC
DOI: 10.1089/vbz.2013.1365
关键词
Lyme disease; Lyme borreliosis; Erythema migrans; Southern tick-associated rash illness (STARI); Borrelia burgdorferi; Ixodes scapularis; Deer tick; Black-legged tick; Amblyomma americanum; Lone star tick; Antibiotics; Doxycycline; Amoxicillin; Cost-effectiveness; Decision analysis
资金
- CDC
- NIH
- Immunetics, Inc.
- Bio-Rad
- DiaSorin, Inc.
- BioMerieux
The skin lesion of early Lyme disease, erythema migrans (EM), is so characteristic that routine practice is to treat all such patients with antibiotics. Because other skin lesions may resemble EM, it is not known whether presumptive treatment of EM is appropriate in regions where Lyme disease is rare. We constructed a decision model to compare the cost and clinical effectiveness of three strategies for the management of EM: Treat All, Observe, and Serology as a function of the probability that an EM-like lesion is Lyme disease. Treat All was found to be the preferred strategy in regions that are endemic for Lyme disease. Where Lyme disease is rare, Observe is the preferred strategy, as presumptive treatment would be expected to produce excessive harm and increased costs. Where Lyme disease is rare, clinicians and public health officials should consider observing patients with EM-like lesions who lack travel to Lyme disease-endemic areas.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据