期刊
VECTOR-BORNE AND ZOONOTIC DISEASES
卷 12, 期 3, 页码 175-182出版社
MARY ANN LIEBERT INC
DOI: 10.1089/vbz.2011.0614
关键词
Amblyomma maculatum; Candidatus Rickettsia andeanae; Gulf Coast Tick; Quantitative real-time PCR Assays; Rickettsia parkeri; Spotted Fever Rickettsioses
资金
- AFHSC-GEIS [0000188M.0931.001.A0074]
Rickettsia parkeri, a spotted fever group (SFG) rickettsia recently found to be pathogenic to humans, causes an eschar-associated febrile illness. The R. parkeri rickettsiosis, Tidewater spotted fever, has been misdiagnosed as Rocky Mountain spotted fever due to serologic cross reactivity and the lack of specific diagnostic methods. Candidatus Rickettsia andeanae, also a SFG rickettsia, is a recently described agent of unknown pathogenicity originally identified in ticks collected from domestic animals during a fever outbreak investigation in northern Peru. Among 37 Amblyomma maculatum (collected from humans (n = 35) and questing (n = 2)) obtained from the southern United States during 2000-2009, nine and four A. maculatum nucleic acid preparations were found positive for R. parkeri and Candidatus R. andeanae, respectively, by newly developed genus-and species-specific quantitative real-time polymerase chain reaction assays. In addition Rickettsia felis was found in two A. maculatum nucleic acid preparations.
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