期刊
VACCINE
卷 26, 期 -, 页码 L1-L15出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.vaccine.2008.05.043
关键词
Anogenital cancer; Cervical cancer; HPV; Oro-pharyrnx cancer; Genital warts; Latin America; Caribbean; Recurrent Respiratory Papilomatosis
We present the burden of human papillomavirus (HPV)-related cancers (cancers of the cervix, anogenital region, oral cavity and pharynx) in terms of incidence and mortality, for the countries of the Latin America and Caribbean region. The region is a high-risk area for cancer of the cervix and, although incidence has declined since the 1960s, projected demographic changes imply that the actual burden of new cases will increase by more than 75% in the next 20 years, while the average and at diagnosis will increase. Approximately 65% of cervical cancer cases and 50% of the high risk lesions are associated with HPV-16 and 18. Incidence rates of other HPV-related cancers are significantly lower. The paper also describes the estimated impact of genital warts and the limited data available on the ocurrence of HPV infections of the upper aerodigestive tract in the region. (C) 2008 Elsevier Ltd. All rights reserved.
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