期刊
UROLOGY
卷 84, 期 4, 页码 815-820出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.urology.2014.03.021
关键词
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资金
- National Key Technology Research and Development Program [2011BAI17B00]
- National Basic Research Program of China (973 Program) [2011CB944502]
- Improving assisted reproductive technology clinical outcome with traditional Chinese drug named Unicorn-pellet (Shandong University) [12220011281307]
OBJECTIVE To investigate the association between testicular microlithiasis (TM) and semen parameters in Chinese adult men with fertility intention. MATERIALS AND METHODS We retrospectively reviewed the ultrasonography results of the reproductive system of 16,204 consecutive adult male patients in our hospital with fertility intention from November 2012 to October 2013. TM was diagnosed by scrotal ultrasonography. Patients with TM were divided into classic testicular microlithiasis (CTM) or limited testicular microlithiasis (LTM). The clinical data of CTM, LTM, and non-TM groups, especially of patients in whom sperms were found in semen analysis, were collected and analyzed. RESULTS There were 226 men (1.39%) diagnosed with TM. The mean age was 28.96 +/- 5.12 years (range, 21-46 years), whereas mean testicular volume was 15.38 +/- 4.90 mL (range, 1.62-31.23 mL). CTM and LTM were detected in 141 (62.39%) and 85 patients (37.61%), respectively. Among 200 patients who underwent semen analysis, sperms were found in 159 men (79.5%; 97 men with CTM and 62 men with LTM). One hundred and twenty cases without TM (ie, non-TM group) were collected in the control group. Sperm concentration, total motility, and percentage of progressively motile of CTM, LTM, and non-TM groups was (38.01 +/- 31.58 million/mL vs 52.31 +/- 33.26 million/mL vs 67.16 +/- 36.94 million/mL; P < .001), (46.03 +/- 23.69% vs 55.37 +/- 24.16% vs 62.08 +/- 20.45%; P < .001), and (35.88 +/- 20.17% vs 43.15 +/- 21.08% vs 47.10 +/- 17.84%; P < .001), respectively. CONCLUSION TM is associated with worse semen parameters in adult men with fertility intention. The extent of microlithiasis correlates inversely with semen parameters. (C) 2014 Elsevier Inc.
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