期刊
UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS
卷 32, 期 5, 页码 537-538出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.urolonc.2013.08.001
关键词
Calcium channel blockers; Prostate cancer
The relationship between calcium channel blockers and prostate cancer has been an area of increased interest to investigators. Calcium channel blockers have been shown to influence cell proliferation, differentiation, and apoptosis. Clinically, the association between calcium channel blockers and the development of prostate cancer has been controversial. However, on a basic science level, there is evidence that calcium channel blockers induce cytotoxicity in androgen receptor positive cell lines and may offer an innovative strategy for the treatment of castration-resistant prostate cancer. (C) 2014 Elsevier Inc. All rights reserved.
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