期刊
ULTRASOUND IN OBSTETRICS & GYNECOLOGY
卷 32, 期 6, 页码 832-834出版社
WILEY
DOI: 10.1002/uog.6221
关键词
blood chimerism; karyotypes; monochorionic twins; twin-twin transfusion syndrome; zygocity determination
We report a case of a dizygotic monochorionic twin Pregnancy preceded by intracytoplasmic sperm injection treatment including assisted hatching. On ultrasound examination at 25 weeks gestation the twins, which had been assumed to be monochorionic, were found to be of different sexes. Karyotyping and Zygocity determination were performed on amniotic fluid and showed the twins to be dizygotic with normal female and male karyotypes. There were Clinical and sonographic signs of twin-twin transfusion syndrome (TTTS), and Cesarean delivery was performed at 32 weeks gestation. At birth the twins were phenotypically a normal male and a normal female. Histology of the placenta showed it to be monochorionic diamniotic. Blood chimerism was found postnatally as both infants bad the karyotypes 46,XX[13]/46,XY[17]. Chimerism was not found in cells from a buccal swab at 6 months of age. This is one of only a few reported cases of dizygotic. C monochorionic twins. Nearly all of these cases have been conceived alter assisted reproductive technology procedures. It is of clinical importance to be aware of this rare phenomenon in relation to TTTS, prenatal screening and parental counseling. Copyright (c) 2008 ISUOG. Published by John Wiley & Sons, Ltd.
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