期刊
ULTRASOUND IN MEDICINE AND BIOLOGY
卷 40, 期 9, 页码 1923-1933出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.ultrasmedbio.2014.03.021
关键词
Liver fibrosis; Real-time elastography; Elastic ratio; Fibrosis index
Despite its invasiveness, liver biopsy is still considered the gold standard for the assessment of hepatic fibrosis. Non-invasive ultrasound-based techniques are increasingly employed to assess parenchymal stiffness and the progression of chronic diffuse liver diseases. Real-time elastography is a rapidly evolving technique that can reveal the elastic properties of tissues. This review examines qualitative and semi-quantitative methods developed for analysis of real-time liver elastograms, to estimate parenchymal stiffness and, indirectly, the stage of fibrosis. Qualitative analysis is the most immediate approach for elastogram analysis, but this method increases intra-and inter-observer variability, which is seen as a major limitation of real-time elastography. Semi-quantitative methods include analysis of the histogram derived from color-coded maps, as well as calculation of the elastic ratio and fibrosis index. (E-mail: Francesco.paparo@galliera.it) (C) 2014 World Federation for Ultrasound in Medicine & Biology.
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