期刊
ULTRASOUND IN MEDICINE AND BIOLOGY
卷 38, 期 6, 页码 1004-1010出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.ultrasmedbio.2012.02.015
关键词
Identity (ID); Nonidentity (NonID); Ovarian; Stimulation; Follicle; Growth; Ultrasound
The objective of this study was to validate the use of the nonidentity (NonID) method compared with the identity (ID) method for tracking the day-to-day growth of individual follicles in women undergoing ovarian stimulation for assisted reproduction. A retrospective observational study was conducted in 20 women during ovarian stimulation. Conventional 2-D transvaginal ultrasonography was used to monitor follicle growth every 2-3 days throughout stimulation. Video clips of both ovaries were obtained in sagittal and coronal planes at each visit. Standardized diameter measurements of all follicles >= 4 mm were made retrospectively from video clips. The growth profiles of all follicles that developed to >= 10 mm were determined using the ID and NonID methods. Using Lin's concordance statistics, we documented that agreement between methods was 91% for follicles <10 mm, 96% for follicles 10-15 mm and 99% for follicles >15 mm. Lin's concordance correlation coefficient between the two methods was 0.96 (standard error = 0.003). We concluded that the NonID method is a practical, effective tool for monitoring the day-to-day growth of individual ovarian follicles in women undergoing assisted reproduction. (E-mail: angela.baerwald@usask.ca) (C) 2012 World Federation for Ultrasound in Medicine & Biology.
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