期刊
ULTRASONICS SONOCHEMISTRY
卷 20, 期 6, 页码 1327-1336出版社
ELSEVIER
DOI: 10.1016/j.ultsonch.2013.04.002
关键词
Sonochemistry; Ultrasound (US); Fused heterocycles
Medicinal chemistry has been benefited by combinatorial chemistry and high throughput parallel synthesis. The use of sonochemistry under controlled conditions has been proved beneficial for medicinal chemistry and drug discovery process since it dramatically reduces reaction times, from days or hours to minutes. In addition, sonochemistry synthesis provides higher yields, lower cost, easy workups and greater purity as compared to lower yields, tedious workups, longer reaction times, lesser purity and termination of many by-products in the conventional thermal methods. (C) 2013 Elsevier B.V. All rights reserved.
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