Investigations on the demetalation of metalloporphyrins under ultrasound irradiation

An efficiently facile method for the demetalation from metalloporphyrins has been developed, which uses high-intensity ultrasound to initiate the ligand dissociation in a mixed solvent of (CH3CO)(2)O/HCl with FeSO4. The influences of substituents, bath temperature and reaction time on the reactions were also investigated, on the base of which the mechanism of demetalation and the effect of ultrasound irradiation on metal-ligand cleavage have been discussed in detail. (C) 2010 Elsevier B.V. All rights reserved.