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V. B. Sulimov et al.
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Charles Frost et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2013)
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Alexey V. Sulimov et al.
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Hannes G. Wallnoefer et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2011)
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Shome S. Bhunia et al.
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Anton Lindstrom et al.
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Elena I. Sinauridze et al.
PLOS ONE (2011)
Analyzing the Topology of Active Sites: On the Prediction of Pockets and Subpockets
Andrea Volkamer et al.
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Factor Xa Inhibitors: Next-Generation Antithrombotic Agents
Donald J. P. Pinto et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
Aroylguanidine-based factor Xa inhibitors: The discovery of BMS-344577
Yan Shi et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2009)
Comparative Pharmacodynamics and Pharmacokinetics of Oral Direct Thrombin and Factor Xa Inhibitors in Development
Bengt I. Eriksson et al.
CLINICAL PHARMACOKINETICS (2009)
DU-176b, a potent and orally active factor Xa inhibitor:: in vitro and in vivo pharmacological profiles
T. Furugohri et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2008)
A dose escalation study of YM150, an oral direct factor Xa inhibitor, in the prevention of venous thromboembolism in elective primary hip replacement surgery
B. I. Eriksson et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2007)
Oral, direct Factor Xa inhibitors in development for the prevention and treatment of thromboembolic diseases
Alexander G. G. Turpie
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2007)
The discovery of the factor Xa inhibitor otamixaban: From lead identification to clinical development
Kevin R. Guertin et al.
CURRENT MEDICINAL CHEMISTRY (2007)
Arylsulfonamides: A study of the relationship between activity and conformational preferences for a series of factor Xa inhibitors
Stefan Senger et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2006)
Review of the rebound phenomenon in new anticoagulant treatments
C Hermans et al.
CURRENT MEDICAL RESEARCH AND OPINION (2006)
New anticoagulants: Anti IIa vs anti Xa - Is one better?
KA Bauer
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Probing the subpockets of factor Xa reveals two binding modes for inhibitors based on a 2-carboxyindole scaffold:: A study combining structure-activity relationship and X-ray crystallography
M Nazaré et al.
JOURNAL OF MEDICINAL CHEMISTRY (2005)
Design of novel and selective inhibitors of urokinase-type plasminogen activator with improved pharmacokinetic properties for use as antimetastatic agents
A Schweinitz et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Surface generalized born method: A simple, fast, and precise implicit solvent model beyond the coulomb approximation
AN Romanov et al.
JOURNAL OF PHYSICAL CHEMISTRY A (2004)
Finding more needles in the haystack: A simple and efficient method for improving high-throughput docking results
AE Klon et al.
JOURNAL OF MEDICINAL CHEMISTRY (2004)
Analyses of activity for factor Xa inhibitors based on Monte Carlo simulations
D Ostrovsky et al.
JOURNAL OF MEDICINAL CHEMISTRY (2003)
What is all that thrombin for?
KG Mann et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2003)
Rational design, synthesis, and structure-activity relationships of novel factor Xa inhibitors: (2-substituted-4-amidinophenyl)pyruvic and -propionic acids
K Sagi et al.
JOURNAL OF MEDICINAL CHEMISTRY (2003)
Can the calculation of ligand binding free energies be improved with continuum solvent electrostatics and an ideal-gas entropy correction?
SM Schwarzl et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2002)
4-aminoarylguanidine and 4-aminobenzamidine derivatives as potent and selective urokinase-type plasminogen activator inhibitors
JR Spencer et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2002)
Design and quantitative structure-activity relationship of 3-amidinobenzyl-1H-indole-2-carboxamides as potent, nonchiral, and selective inhibitors of blood coagulation factor Xa
H Matter et al.
JOURNAL OF MEDICINAL CHEMISTRY (2002)
4-Amidinobenzylamine-based inhibitors of urokinase
S Künzel et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2002)
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