Towards ETEM serial crystallography: Electron diffraction from liquid jets

A sufficiently thin column of liquid was produced to permit penetration with a 200 key electron beam as evidenced by the observation of diffraction rings due to the intermolecular spacing of the liquid samples. For liquid thickness below 800 nm, the diffraction rings became visible above the inelastic background. Studies were carried out in the environmental chamber of a transmission electron microscope using water and isopropanol. (C) 2010 Elsevier B.V. All rights reserved.