期刊
TUMOR BIOLOGY
卷 36, 期 1, 页码 41-53出版社
SAGE PUBLICATIONS LTD
DOI: 10.1007/s13277-014-2818-8
关键词
Cancer; Small nucleolar RNAs; Non-coding RNAs; GAS5
类别
资金
- project Employment of Best Young Scientists for International Cooperation Empowerment [CZ.1.07/2.3.00/30.0037]
- European Social Fund
- state budget of the Czech Republic, by the project CEITEC-Central European Institute of Technology [CZ.1.05/1.1.00/02.0068]
- project MZ CR-RVO [MOU, 00209805]
Non-coding RNAs (ncRNAs) are important regulatory molecules involved in various physiological and pathological cellular processes. Small nucleolar RNAs (snoRNAs), subclass of small ncRNAs, have been considered important but unglamorous elements in the production of protein synthesis machinery of cells. However, recent evidence has indicated that these non-coding RNAs might have a crucial role also in controlling cell behavior, and snoRNAs dysfunction could significantly contribute to carcinogenesis. Here, we summarize the most important aspects of snoRNAs biology, their functioning in cancer cell, and potential usage in diagnosis or as a new class of therapeutic targets in cancer.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据