期刊
BIOMATERIALS SCIENCE
卷 3, 期 4, 页码 586-591出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4bm00416g
关键词
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资金
- Centre for Clinical Research University Hospital
- ETH Zurich
- University of Zurich
We report that stiffness gradients facilitate infiltration of cells through otherwise cell-impermeable hydrogel interfaces. By enabling the separation of hydrogel manufacturing and cell seeding, and by improving cell colonization of additively manufactured hydrogel elements, interfacial density gradients present a promising strategy to progress in the creation of 3D tissue models.
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