期刊
TRIBOLOGY INTERNATIONAL
卷 46, 期 1, 页码 215-224出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.triboint.2011.06.035
关键词
Hydrogel; p(HEMA); Articular cartilage; Mechanical properties
资金
- French Government
- Embassy of France in Romania
Poly(hydroxyethyl methacrylate) (p(HEMA)) hydrogels have been proposed as promising biomaterials to replace damaged articular cartilage. A major obstacle to their use as replacement bearing tissue is their poor mechanical properties in comparison with healthy articular cartilage. The purpose of this study was to obtain p(HEMA) hydrogels with physicochemical and mechanical properties close to healthy articular cartilage, by introducing a hydrophilic monomer, namely acrylic acid (AA). Formulations of hydrogels with different amounts of hydrophilic monomer (acrylic acid, AA) were synthesized and tested: p(HEMA), p(HEMA-co-5%AA), p(HEMA-co-25%AA). The macro-mechanical tests were reproduced at nanoscale in order to verify if the superficial properties of the hydrogels are similar to the bulk ones. Crown Copyright (C) 2011 Published by Elsevier Ltd. All rights reserved.
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