相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Rest versus exercise as treatment for patients with low back pain and Modic changes. a randomized controlled clinical trial
Rikke K. Jensen et al.
BMC MEDICINE (2012)
Efficacy and tolerability of rizatriptan in pediatric migraineurs: Results from a randomized, double-blind, placebo-controlled trial using a novel adaptive enrichment design
Tony W. Ho et al.
CEPHALALGIA (2012)
Phase I study of continuous MKC-1 in patients with advanced or metastatic solid malignancies using the modified Time-to-Event Continual Reassessment Method (TITE-CRM) dose escalation design
Amye Tevaarwerk et al.
INVESTIGATIONAL NEW DRUGS (2012)
ADAPTIVE RANDOMIZATION FOR CLINICAL TRIALS
William F. Rosenberger et al.
JOURNAL OF BIOPHARMACEUTICAL STATISTICS (2012)
Design Issues in Randomized Phase II/III Trials
Edward L. Korn et al.
JOURNAL OF CLINICAL ONCOLOGY (2012)
NeuroNEXT: accelerating drug development in neurology
[Anonymous]
LANCET NEUROLOGY (2012)
Potential of adaptive clinical trial designs in pharmacogenetic research
Frederieke H. van der Baan et al.
PHARMACOGENOMICS (2012)
The covariate-adaptive biased coin design for balancing clinical trials in the presence of prognostic factors
A. Baldi Antognini et al.
BIOMETRIKA (2011)
A point-of-care clinical trial comparing insulin administered using a sliding scale versus a weight-based regimen
Louis D. Fiore et al.
CLINICAL TRIALS (2011)
Outcome-Adaptive Randomization: Is It Useful?
Edward L. Korn et al.
JOURNAL OF CLINICAL ONCOLOGY (2011)
FOLFIRINOX versus Gemcitabine for Metastatic Pancreatic Cancer
Thierry Conroy et al.
NEW ENGLAND JOURNAL OF MEDICINE (2011)
Benefits, challenges and obstacles of adaptive clinical trial designs
Shein-Chung Chow et al.
ORPHANET JOURNAL OF RARE DISEASES (2011)
Blinded sample size recalculation for clinical trials with normal data and baseline adjusted analysis
Tim Friede et al.
PHARMACEUTICAL STATISTICS (2011)
Seamless phase II/III designs
Nigel Stallard et al.
STATISTICAL METHODS IN MEDICAL RESEARCH (2011)
Adaptive increase in sample size when interim results are promising: A practical guide with examples
Cyrus R. Mehta et al.
STATISTICS IN MEDICINE (2011)
A Bayesian response-adaptive covariate-balanced randomization design with application to a leukemia clinical trial
Ying Yuan et al.
STATISTICS IN MEDICINE (2011)
Safety and Tolerability of Deferoxamine Mesylate in Patients With Acute Intracerebral Hemorrhage
Magdy Selim et al.
STROKE (2011)
Efficiency Perspectives on Adaptive Designs in Stroke Clinical Trials
Ken Cheung et al.
STROKE (2011)
Internal pilots for observational studies
Matthew J. Gurka et al.
BIOMETRICAL JOURNAL (2010)
A simulation study for comparing testing statistics in response-adaptive randomization
Xuemin Gu et al.
BMC MEDICAL RESEARCH METHODOLOGY (2010)
Enrichment of Clinical Study Populations
R. Temple
CLINICAL PHARMACOLOGY & THERAPEUTICS (2010)
Combining an Internal Pilot with an Interim Analysis for Single Degree of Freedom Tests
John A. Kairalla et al.
COMMUNICATIONS IN STATISTICS-THEORY AND METHODS (2010)
Adaptive Methods: Telling The Rest of the Story
Scott S. Emerson et al.
JOURNAL OF BIOPHARMACEUTICAL STATISTICS (2010)
Comparative effectiveness research: Policy context, methods development and research infrastructure
Sean R. Tunis et al.
STATISTICS IN MEDICINE (2010)
The Bias Issue Under the Complete Null With Response Adaptive Randomization: Commentary on Adaptive and Model-Based Dose-Ranging Trials: Quantitative Evaluation and Recommendation
Sue-Jane Wang
STATISTICS IN BIOPHARMACEUTICAL RESEARCH (2010)
Phase II Trial of CoQ10 for ALS Finds Insufficient Evidence to Justify Phase III
Petra Kaufmann et al.
ANNALS OF NEUROLOGY (2009)
Adaptive patient enrichment designs in therapeutic trials
Sue-Jane Wang et al.
BIOMETRICAL JOURNAL (2009)
Sample size re-estimation in clinical trials
Michael A. Proschan
BIOMETRICAL JOURNAL (2009)
High-Dose Lovastatin for Acute Ischemic Stroke: Results of the Phase I Dose Escalation Neuroprotection with Statin Therapy for Acute Recovery Trial (NeuSTART)
Mitchell S. V. Elkind et al.
CEREBROVASCULAR DISEASES (2009)
Planning and Executing Response-Adaptive Learn-Phase Clinical Trials: 1. The Process
Parvin Fardipour et al.
DRUG INFORMATION JOURNAL (2009)
Dose Escalation Methods in Phase I Cancer Clinical Trials
Christophe Le Tourneau et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2009)
Adaptive designs for confirmatory clinical trials
Frank Bretz et al.
STATISTICS IN MEDICINE (2009)
Group sequential and adaptive designs - A review of basic concepts and points of discussion
Marc Vandemeulebroecke
BIOMETRICAL JOURNAL (2008)
Handling Covariates in the Design of Clinical Trials
William F. Rosenberger et al.
STATISTICAL SCIENCE (2008)
Adaptive clinical trials - Progress and challenges
Christopher S. Coffey et al.
DRUGS IN R&D (2008)
Multiplicity and flexibility in clinical trials
Werner Brannath et al.
PHARMACEUTICAL STATISTICS (2007)
Innovative approaches for designing and analyzing adaptive dose-ranging trials
Bjoern Bornkamp et al.
JOURNAL OF BIOPHARMACEUTICAL STATISTICS (2007)
Practical methods for bounding type I error rate with an internal pilot design
Christopher S. Coffey et al.
COMMUNICATIONS IN STATISTICS-THEORY AND METHODS (2007)
The design of simulation studies in medical statistics
Andrea Burton et al.
STATISTICS IN MEDICINE (2006)
Information-based monitoring of clinical trials
Anastasios A. Tsiatis
STATISTICS IN MEDICINE (2006)
Sample size recalculation in internal pilot study designs: A review
Tim Friede et al.
BIOMETRICAL JOURNAL (2006)
Adaptive designs in clinical drug development - An Executive Summary of the PhRMA Working Group
Paul Gallo et al.
JOURNAL OF BIOPHARMACEUTICAL STATISTICS (2006)
Efficient group sequential designs when there are several effect sizes under consideration
C Jennison et al.
STATISTICS IN MEDICINE (2006)
A two-stage design for a phase II clinical trial of coenzyme Q10 in ALS
G Levy et al.
NEUROLOGY (2006)
The continual reassessment method for dose-finding studies: a tutorial
E Garrett-Mayer
CLINICAL TRIALS (2006)
Evaluation of randomized discontinuation design
B Freidlin et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
Two-stage sample size re-estimation based on a nuisance parameter: A review
MA Proschan
JOURNAL OF BIOPHARMACEUTICAL STATISTICS (2005)
On the inefficiency of the adaptive design for monitoring clinical trials
AA Tsiatis et al.
BIOMETRIKA (2003)
Acute Stroke Therapy by Inhibition of Neutrophils (ASTIN) - An adaptive dose-response study of UK-279,276 in acute ischemic stroke
M Krams et al.
STROKE (2003)
Controlling test size while gaining the benefits of an internal pilot design
CS Coffey et al.
BIOMETRICS (2001)
分享论文
