期刊
TRENDS IN PLANT SCIENCE
卷 14, 期 2, 页码 92-99出版社
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tplants.2008.11.008
关键词
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资金
- Biotechnology and Biological Sciences Research Council [P17237] Funding Source: researchfish
- Biotechnology and Biological Sciences Research Council [P17237] Funding Source: Medline
N-glycosylation is a complex process that encompasses the biosynthesis and modification of sugar moieties in the endoplasmic reticulum (ER) and Golgi. The ER-localized steps of N-glycan production in plants have received relatively little attention, despite their emerging roles in stress responses. Here, we integrate information on the molecular components underlying the three stages of N-glycan production: lipid-linked oligosaccharide synthesis, co-translational oligosaccharyl-transfer and quality control of the folded glycoprotein in the ER. The relative importance of each step for N-glycosylation and plant performance is evaluated on the basis of studies with inhibitors and mutant phenotypes. Finally, we highlight the increasing evidence for crosstalk between N-glycan production and defence responses in plants and discuss the practical implications for pathogen resistance.
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