期刊
TRENDS IN PLANT SCIENCE
卷 13, 期 7, 页码 368-374出版社
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tplants.2008.03.008
关键词
-
资金
- NIGMS NIH HHS [R01 GM061146, R01 GM061146-09, GM61146] Funding Source: Medline
The Arabidopsis genome encodes two major classes of 20-24-nucleotide riboregulators: microRNAs and small interfering RNAs. These small RNAs act as sequence-specific repressors of target gene expression, either at the transcriptional level through DNA and/or histone methylation or at the post-transcriptional level through transcript cleavage or translational inhibition. Small RNAs are processed from precursor RNAs by one or more of the four DICER-LIKE RNase III enzymes, modified by HUA ENHANCER 1, a small RNA methyltransferase, and loaded onto an argonaute protein-containing RNA-induced silencing complex. Here, we review the biogenesis of small RNAs, and we discuss the major outstanding questions in small RNA metabolism and function.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据