期刊
TRENDS IN PARASITOLOGY
卷 29, 期 1, 页码 35-42出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.pt.2012.09.006
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类别
资金
- Australian Research Council
- Queensland Health Clinical Research Fellowship
- National Health and Medical Research Council
Scabies remains a significant public health problem worldwide. Research into aspects of Sarcoptes scabiei biology and host parasite interactions has been impeded by an inability to maintain mites in vitro and by limited access to parasite material and infected subjects. The generation of comprehensive expressed sequence tag libraries has enabled the initial characterisation of molecules of interest to diagnostics, vaccines, and drug resistance. The recent development and utilisation of animal models, combined with next-generation technologies, is anticipated to lead to new strategies to prevent, diagnose, and treat scabies, ultimately improving skin health in both human and veterinary settings. This article will summarise recent molecular and immunologic advances on scabies, and will address priorities for the exciting 'next chapter' of scabies research.
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