期刊
TRENDS IN PARASITOLOGY
卷 29, 期 4, 页码 197-205出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.pt.2013.02.001
关键词
neglected tropical diseases; preventive chemotherapy; paediatrics; praziguantel; cure rates; pharmacokinetics; malaria; HIV
类别
资金
- Wellcome Trust, UK
The occurrence of schistosomiasis within African infants and preschool children has been much better documented in recent years, revealing an important burden of disease previously overlooked. Despite mounting evidence showing that treatment with praziquantel is safe, beneficial, and could be delivered within ongoing public health interventions, young children still do not have satisfactory access to this drug, and a significant treatment gap exists. Progress towards resolution of this unfortunate health inequity is highlighted, including the development of an appropriate paediatric praziquantel formulation, and present blocks are identified on securing this issue within the international health agenda.
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