期刊
TRENDS IN PARASITOLOGY
卷 27, 期 10, 页码 434-441出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.pt.2011.05.006
关键词
-
类别
资金
- NIAID NIH HHS [R03 AI076762, R03 AI076762-02] Funding Source: Medline
Trypanosome brucei undergoes major biochemical and morphological changes during its development from the bloodstream form in the mammalian host to the procyclic form in the midgut of its insect host. The underlying regulation of gene expression, however, is poorly understood. More than 60% of the predicted genes remain annotated as hypothetical, and the 5' and 3' untranslated regions important for regulation of gene expression are unknown for >90% of the genes. In this review, we compare the data from four recently published high-throughput RNA sequencing studies in light of the different experimental setups and discuss how these data can enhance genome annotation and give insights into the regulation of gene expression in T. brucei.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据