期刊
TRENDS IN MICROBIOLOGY
卷 22, 期 7, 页码 417-424出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.tim.2014.03.008
关键词
bacteria; persisters; pathogens; infection; antibiotic tolerance
资金
- Junior Research Fellowship from Imperial College London
- MRC [MR/J006874/1] Funding Source: UKRI
Persisters are multidrug-tolerant bacteria that could account for the relapse of infections. For a long time, persisters have been assumed to be nonreplicating dormant bacteria, but the growth status of these recalcitrant cells is still debated. Toxin antitoxin (TA) modules have an important role in the formation of persisters and several studies show that they can form in response to different triggers. These findings, together with the invention of new tools to study persisters, could have important implications for the development of novel therapeutics to eradicate persisting subpopulations.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据