期刊
TRENDS IN MICROBIOLOGY
卷 22, 期 9, 页码 536-545出版社
CELL PRESS
DOI: 10.1016/j.tim.2014.05.005
关键词
antibiotic-resistance genes; horizontal gene transfer; rhizosphere
资金
- Deutsche Forschungsgemeinschaft (DFG)
- Umweltbundesamt [3713 63 402]
- [SM59/5-3]
Large amounts of veterinary antibiotics are applied worldwide to farm animals and reach agricultural fields by manure fertilization, where they might lead to an increased abundance and transferability of antibiotic-resistance determinants. In this review we discuss recent advances, limitations, and research needs in determining the fate of veterinary antibiotics and resistant bacteria applied with manure to soil, and their effects on the structure and function of soil microbial communities in bulk soils and the rhizosphere. The increased abundance and mobilization of antibiotic-resistance genes (ARGs) might contribute to the emergence of multi-resistant human pathogens that increasingly threaten the successful antibiotic treatment of bacterial infections.
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