期刊
TRENDS IN MICROBIOLOGY
卷 22, 期 1, 页码 42-47出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.tim.2013.11.003
关键词
methicillin-resistant Staphylococcus aureus (MESA); mecC; zoonosis; antibiotic resistance; molecular epidemiology; genome sequencing
资金
- Medical Research Council (MRC)
- PetPlan Charitable Trust
- British Society for Antimicrobial Chemotherapy
- Cambridge-Africa Alborada Research Fund
- Medical Research Council [G1001787] Funding Source: researchfish
- MRC [G1001787] Funding Source: UKRI
The report of methicillin-resistant Staphylococcus aureus (MRSA) encoding a divergent mecA gene in 2011 was highly significant. This homologue, designated mecC, poses diagnostic problems with the potential to be misdiagnosed as methicillin-sensitive S. aureus, with important potential consequences for individual patients and for the surveillance of MRSA. mecC MRSA have now been reported from 13 European countries and have been isolated from 14 different host species, with evidence of a recent increase in Denmark. The emergence of mecC MRSA is a topic of interest to human and veterinary microbiology, and we consider it timely to review here its discovery and subsequent investigation.
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