期刊
TRENDS IN MICROBIOLOGY
卷 20, 期 5, 页码 235-242出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.tim.2012.02.008
关键词
di-nucleotide signaling; signal transduction; biofilm formation; pathogenesis; virulence
资金
- Science Foundation of Ireland (SFI) [07/IN.1/B955, 09/SIRG/B1654]
- Science Foundation of Ireland through Royal Irish Academy
- Danish Research Council
- Science Foundation Ireland (SFI) [07/IN.1/B955, 09/SIRG/B1654] Funding Source: Science Foundation Ireland (SFI)
The second messenger cyclic di-GMP has emerged as a central regulator of many important bacterial processes including biofilm formation and virulence. Although the pathways of cyclic di-GMP synthesis and degradation have been established, the mechanisms by which this second messenger exerts its action on diverse cellular functions remain relatively poorly understood. Recent studies report considerable advances in identifying different classes of cyclic di-GMP effectors; these include the PilZ protein domain, transcription factors, proteins involved in RNA processing and riboswitches. Here, we review this range of cyclic di-GMP effectors and the biological processes that they govern using examples from several different bacteria.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据