期刊
TRENDS IN MICROBIOLOGY
卷 16, 期 10, 页码 496-506出版社
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tim.2008.07.004
关键词
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资金
- Fund for Scientific Research - Flanders (FWO) [G.0637.06]
- K.U.Leuven Research Council [IDO/05/012, GOA/2003/09]
Swarming is the fastest known bacterial mode of surface translocation and enables the rapid colonization of a nutrient-rich environment and host tissues. This complex multicellular behavior requires the integration of chemical and physical signals, which leads to the physiological and morphological differentiation of the bacteria into swarmer cells. Here, we provide a review of recent advances in the study of the regulatory pathways that lead to swarming behavior of different model bacteria. It has now become clear that many of these pathways also affect the formation of biofilms, surface-attached bacterial colonies. Decision-making between rapidly colonizing a surface and biofilm formation is central to bacterial survival among competitors. In the second part of this article, we review recent developments in the understanding of the transition between motile and sessile lifestyles of bacteria.
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