期刊
TRENDS IN GENETICS
卷 34, 期 9, 页码 722-732出版社
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tig.2018.06.003
关键词
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资金
- National Science Foundation Graduate Research Fellowship Program [DGE-1313190]
- Eunice Kennedy Shriver National Institute of Child Health and Human Development [R01-HD073439, R01-HD094787]
- National Institute of General Medical Sciences [R01-GM098536]
- EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT [R01HD073439, R01HD094787] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM098536] Funding Source: NIH RePORTER
Developmental constraint and sexual conflict shape the evolution of heteromorphic sex chromosomes. These contrasting forces are perhaps strongest during spermatogenesis in species with XY males. In this review, we consider how the unique regulatory environment and selective pressures of spermatogenesis interact to impact sex chromosome evolution in mammals. We explore how each developmental phase of spermatogenesis influences sex chromosome gene content, structure, and rate of molecular evolution, and how these attributes may contribute to speciation. We argue that a developmental context is fundamental to understanding sex chromosome evolution and that an evolutionary perspective can shed new light on our understanding of sperm development.
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