期刊
TRENDS IN COGNITIVE SCIENCES
卷 17, 期 5, 页码 241-254出版社
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tics.2013.03.003
关键词
cerebellum; cerebral cortex; basal ganglia; non-motor function; transneuronal tracers
资金
- Office of Research and Development, Medical Research Service, Department of Veterans Affairs
- National Institutes of Health [R01 NS24328, R01 MH56661, P40 OD010996, P30 NS076405]
The dominant view of cerebellar function has been that it is exclusively concerned with motor control and coordination. Recent findings from neuroanatomical, behavioral, and imaging studies have profoundly changed this view. Neuroanatomical studies using virus transneuronal tracers have demonstrated that cerebellar output reaches vast areas of the neocortex, including regions of prefrontal and posterior parietal cortex. Furthermore, it has recently become clear that the cerebellum is reciprocally connected with the basal ganglia, which suggests that the two subcortical structures are part of a densely interconnected network. Taken together, these findings elucidate the neuroanatomical substrate for cerebellar involvement in non-motor functions mediated by the prefrontal and posterior parietal cortex, as well as in processes traditionally associated with the basal ganglia.
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