期刊
TRENDS IN CELL BIOLOGY
卷 24, 期 9, 页码 537-545出版社
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tcb.2014.04.004
关键词
endoplasmic reticulum; mitochondria; organelle contact sites; peroxisomes; plasma membrane
类别
资金
- Deutsche Forschungsgemeinschaft (DFG)
Mitochondria are highly dynamic organelles. During their life cycle they frequently fuse and divide, and damaged mitochondria are removed by autophagic degradation. These processes serve to maintain mitochondrial function and ensure optimal energy supply for the cell. It has recently become clear that this complex mitochondrial behavior is governed to a large extent by interactions with other organelles. In this review, we describe mitochondrial contacts with the endoplasmic reticulum (ER), plasma membrane, and peroxisomes. In particular, we highlight how mitochondrial fission, distribution, inheritance, and turnover are orchestrated by interorganellar contacts in yeast and metazoa. These interactions are pivotal for the integration of the dynamic mitochondrial network into the architecture of eukaryotic cells.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据