期刊
TRENDS IN CELL BIOLOGY
卷 23, 期 2, 页码 47-53出版社
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tcb.2012.09.006
关键词
membrane tension; motility; cell shape
类别
资金
- NIH [GM084040, GM074751]
Many cell phenomena that involve shape changes are affected by the intrinsic deformability of the plasma membrane (PM). Far from being a passive participant, the PM is now known to physically, as well as biochemically, influence cell processes ranging from vesicle trafficking to actin assembly. Here we review current understanding of how changes in PM tension regulate cell shape and movement, as well as how cells sense PM tension.
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