期刊
TRENDS IN BIOTECHNOLOGY
卷 36, 期 12, 页码 1259-1274出版社
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tibtech.2018.07.007
关键词
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资金
- National Institutes of Health [GM126831]
- University of Nebraska-Lincoln
- Nebraska Tobacco Settlement Biomedical Research Enhancement Funds
Chronic non-healing wounds aremajor healthcare challenges that affect a noticeable number of people; they exert a severe financial burden and are the leading cause of limb amputation. Although chronic wounds are locked in a persisting inflamed state, they are dynamic and proper therapy requires identifying abnormalities, administering proper drugs and growth factors, and modulating the conditions of the environment. In this review article, we discuss technologies that have been developed to actively monitor the wound environment. We also highlight drug delivery tools that have been integrated with bandages to facilitate precise temporal and spatial control over drug release and review automated or semi-automated systems that can respond to the wound environment.
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