期刊
TRENDS IN BIOTECHNOLOGY
卷 32, 期 12, 页码 627-636出版社
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tibtech.2014.09.009
关键词
high-throughput; combinatorial; biomaterials; lab-on-chip testing; arrays
资金
- Fundacao para a Ciencia e a Tecnologia (FCT) [SFRH/BD/71396/2010]
- Fundo Europeu de Desenvolvimento Regional (FEDER) through the Competitive Factors Operation Program Programa Operacional Factores de Competitividade (COMPETE)
- FCT [PTDC/CTM-BIO/1814/2012]
- Fundação para a Ciência e a Tecnologia [SFRH/BD/71396/2010] Funding Source: FCT
With the increasing need for biomaterials and tissue engineering alternatives, more accurate, rapid, and cost-saving methods and models to study biomaterial cell interactions must be developed. We review the evolution of microarray platforms used for such studies in order to meet the criteria of complex tissue engineering biological environments. Particular aspects regarding biomaterials processing, data acquisition, and treatment are addressed. Apart from in vitro array-based strategies, we also address emerging in vivo high-throughput approaches and their associated trends, such as the role of inflammation in regeneration. The up-scaling of high-throughput methods using single cell encapsulation systems is also explored. Possible limitations related to the use of such methods, such as spot-to-spot crosstalk, are also discussed.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据