期刊
TRENDS IN BIOTECHNOLOGY
卷 32, 期 11, 页码 564-570出版社
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tibtech.2014.09.001
关键词
hydrogel; electrospinning; mechanical testing; biocompatibility; nanofibers; composites
资金
- Engineering and Physical Sciences Research Council (EPSRC)
- Engineering and Physical Sciences Research Council (EPSRC) via the Nano Science and Technology Doctoral Training Centre (NanoDTC) [EP/G037221/1]
- Engineering and Physical Sciences Research Council [1354760] Funding Source: researchfish
Hydrogels closely resemble the extracellular matrix (ECM) and can support cell proliferation while new tissue is formed, making them materials of choice as tissue engineering scaffolds. However, their sometimes-poor mechanical properties can hinder their application. The addition of meshes of nanofibers embedded in their matrix forms a composite that draws from the advantages of both components. Given that these materials are still in the early stages of development, there is a lack of uniformity across methods for characterizing their mechanical properties. Here, we propose a simple metric to enable comparisons between materials. The fibrous constituent improves the mechanical properties of the hydrogel, while the biocompatibility and functionality of the gels are maintained or even improved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据