期刊
TRENDS IN BIOTECHNOLOGY
卷 28, 期 4, 页码 189-197出版社
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tibtech.2009.12.006
关键词
-
资金
- Genetically Engineered Materials Science & Engineering Center (GEMSEC)
- NSF-Materials Research Science & Engineering Center (NSF-MRSEC) at the University of Washington, Seattle
- University of Washington Engineered Biomaterials Research Center [NSF-EEC 9529161]
Advances in disease treatment and tissue regeneration are buoyed by new, multifaceted materials that emulate and coercively interact with the local microenvironment. Polyblend nanofibers represent an emerging class of biomimetic nanostructures that can act as proxies of the native tissue, while providing topographical and biochemical cues that promote healing. These fibers are prepared with mixtures of synthetically and naturally derived polymers that can behave cooperatively to demonstrate unique combinations of mechanical, biochemical and structural properties. This flexibility has led to the application of polyblend nanofibers in a wide assortment of tissue engineering and drug delivery systems. In this review, we will examine design criteria and properties of polymer-blend nanofibers and their use in tissue engineering and local therapeutic delivery applications.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据