期刊
TRENDS IN BIOCHEMICAL SCIENCES
卷 36, 期 11, 页码 585-592出版社
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tibs.2011.07.005
关键词
-
资金
- NIH [RO1GM069900, 1R21NS0676601, 5R00GM080447]
- NSF [1020739]
- Welch Foundation [AU-1773]
- Div Of Molecular and Cellular Bioscience
- Direct For Biological Sciences [1020739] Funding Source: National Science Foundation
Defective mRNAs are degraded more rapidly than normal mRNAs in a process called mRNA surveillance. Eukaryotic cells use a variety of mechanisms to detect aberrations in mRNAs and a variety of enzymes to preferentially degrade them. Recent advances in the field of RNA surveillance have provided new information regarding how cells determine which mRNA species should be subject to destruction and novel mechanisms by which a cell tags an mRNA once such a decision has been reached. In this review, we highlight recent progress in our understanding of these processes.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据